Missing Subfolders in Hard Drive Partition, Virus Issue or Hard Drive?

I've run into a problem that seems to be either a hard drive partition problem or some kind of virus. Symptoms include:
1. Subfolders in one of the hard drive partitions are not showing up when I navigate to them. The drive indicates that it is nearly full, however, when I view properties. So it is indicating that the space is occupied, but only a few files at the top level show up.
2. When I do a search for jpeg files on that partition, none of the photo files (that's what is in these subfolders) show up. Only a few at the main folder level.
3. At one point, my Norton antivirus kept turning some of the auto protect features off. I finally uninstalled and re-installed. Seems OK now.
4. Some other photos, like the screen saver, disappeared for a while, then came back, no idea why.
5. Computer seems sluggish.
6. I did do a RAM upgrade just prior to noticing this missing folders issue, however, it had been a few weeks since I looked up those folders, so it may be a coincidence.
7. This is not the C drive that is affected, but the second hard drive where I store music, photo and video files. This drive is also partitioned. The missing folders only appear to be on one of the partiions. The other one seems fine.
8. Some of the antivirus programs appear to not update as well.
9. When I ran disc check I get an error message.

I am running windows xp, SP3 on a Dell Dimension Desktop. It is old, but I had no problems until this recent issue.

Since this issue arose, I have run scans with an updated version of the Norton antivirus, I have run Malwarebytes, spybot. I have restored settings in safe mode to an earlier version, pre-dating the problem. Nothing has worked. The folders are not "hidden" in options.

I've run Hijack this and posted the log below. Any help would be appreciated on this.

Logfile of Trend Micro HijackThis v2.0.4
Scan saved at 9:42:12 AM, on 4/6/2012
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v8.00 (8.00.6001.18702)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\AVAST Software\Avast\AvastSvc.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\ArcSoft\Connection Service\Bin\ACService.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\Program Files\Common Files\Motive\McciCMService.exe
C:\Program Files\Norton Internet Security\Engine\19.6.2.10\ccSvcHst.exe
C:\WINDOWS\system32\NMSSvc.exe
C:\Program Files\Common Files\Roxio Shared\SharedCOM8\RoxMediaDB.exe
C:\Program Files\Common Files\Roxio Shared\SharedCOM8\RoxWatch.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Norton Internet Security\Engine\19.6.2.10\ccSvcHst.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Common Files\ArcSoft\Connection Service\Bin\ACDaemon.exe
C:\Program Files\Adobe\Acrobat 9.0\Acrobat\Acrotray.exe
C:\Program Files\ScanSoft\OmniPageSE\opware32.exe
C:\Program Files\Common Files\ArcSoft\Connection Service\Bin\ArcCon.ac
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\Microsoft IntelliPoint\ipoint.exe
C:\PROGRA~1\MUSICM~1\MUSICM~2\MMDiag.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\AVAST Software\Avast\avastUI.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\MusicMatch\MusicMatch Jukebox\mim.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Microsoft IntelliPoint\dpupdchk.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\WINDOWS\system32\taskmgr.exe
C:\Program Files\Trend Micro\HiJackThis\HiJackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: Norton Identity Protection - {602ADB0E-4AFF-4217-8AA1-95DAC4DFA408} - C:\Program Files\Norton Internet Security\Engine\19.6.2.10\coIEPlg.dll
O2 - BHO: Norton Vulnerability Protection - {6D53EC84-6AAE-4787-AEEE-F4628F01010C} - C:\Program Files\Norton Internet Security\Engine\19.6.2.10\IPS\IPSBHO.DLL
O2 - BHO: avast! WebRep - {8E5E2654-AD2D-48bf-AC2D-D17F00898D06} - C:\Program Files\AVAST Software\Avast\aswWebRepIE.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - C:\Program Files\Google\Google Toolbar\GoogleToolbar_32.dll
O2 - BHO: Adobe PDF Conversion Toolbar Helper - {AE7CD045-E861-484f-8273-0445EE161910} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\5.7.7227.1100\swg.dll
O2 - BHO: SmartSelect - {F4971EE7-DAA0-4053-9964-665D8EE6A077} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll
O3 - Toolbar: Adobe PDF - {47833539-D0C5-4125-9FA8-0819E2EAAC93} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll
O3 - Toolbar: Google Toolbar - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - C:\Program Files\Google\Google Toolbar\GoogleToolbar_32.dll
O3 - Toolbar: avast! WebRep - {8E5E2654-AD2D-48bf-AC2D-D17F00898D06} - C:\Program Files\AVAST Software\Avast\aswWebRepIE.dll
O3 - Toolbar: Norton Toolbar - {7FEBEFE3-6B19-4349-98D2-FFB09D4B49CA} - C:\Program Files\Norton Internet Security\Engine\19.6.2.10\coIEPlg.dll
O4 - HKLM\..\Run: [ArcSoft Connection Service] C:\Program Files\Common Files\ArcSoft\Connection Service\Bin\ACDaemon.exe
O4 - HKLM\..\Run: [Adobe Acrobat Speed Launcher] "C:\Program Files\Adobe\Acrobat 9.0\Acrobat\Acrobat_sl.exe"
O4 - HKLM\..\Run: [Acrobat Assistant 8.0] "C:\Program Files\Adobe\Acrobat 9.0\Acrobat\Acrotray.exe"
O4 - HKLM\..\Run: [MimBoot] C:\PROGRA~1\MUSICM~1\MUSICM~2\mimboot.exe
O4 - HKLM\..\Run: [Omnipage] C:\Program Files\ScanSoft\OmniPageSE\opware32.exe
O4 - HKLM\..\Run: [APSDaemon] "C:\Program Files\Common Files\Apple\Apple Application Support\APSDaemon.exe"
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [IntelliPoint] "C:\Program Files\Microsoft IntelliPoint\ipoint.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [avast] "C:\Program Files\AVAST Software\Avast\avastUI.exe" /nogui
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O8 - Extra context menu item: Append Link Target to Existing PDF - res://C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll/AcroIEAppendSelLinks.html
O8 - Extra context menu item: Append to Existing PDF - res://C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll/AcroIEAppend.html
O8 - Extra context menu item: Convert Link Target to Adobe PDF - res://C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll/AcroIECaptureSelLinks.html
O8 - Extra context menu item: Convert to Adobe PDF - res://C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEFavClient.dll/AcroIECapture.html
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office12\EXCEL.EXE/3000
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\Office12\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/microsof...?1238369893015
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/microsof...?1238369877421
O16 - DPF: {E0FEE963-BB53-4215-81AD-B28C77384644} (WebBrowserType Class) - https://pattcw.att.motive.com/wizlet...tInstaller.cab
O20 - AppInit_DLLs: C:\PROGRA~1\Google\GOOGLE~1\GOEC62~1.DLL
O22 - SharedTaskScheduler: Browseui preloader - {438755C2-A8BA-11D1-B96B-00A0C90312E1} - C:\WINDOWS\System32\browseui.dll
O22 - SharedTaskScheduler: Component Categories cache daemon - {8C7461EF-2B13-11d2-BE35-3078302C2030} - C:\WINDOWS\System32\browseui.dll
O23 - Service: ArcSoft Connect Daemon (ACDaemon) - ArcSoft Inc. - C:\Program Files\Common Files\ArcSoft\Connection Service\Bin\ACService.exe
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\AppleMobileDeviceService.exe
O23 - Service: avast! Antivirus - AVAST Software - C:\Program Files\AVAST Software\Avast\AvastSvc.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: Google Desktop Manager 5.9.911.3589 (GoogleDesktopManager-110309-193829) - Google - C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe
O23 - Service: Google Update Service (gupdate) (gupdate) - Google Inc. - C:\Program Files\Google\Update\GoogleUpdate.exe
O23 - Service: Google Update Service (gupdatem) (gupdatem) - Google Inc. - C:\Program Files\Google\Update\GoogleUpdate.exe
O23 - Service: Google Software Updater (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McciCMService - Alcatel-Lucent - C:\Program Files\Common Files\Motive\McciCMService.exe
O23 - Service: Norton Internet Security (NIS) - Symantec Corporation - C:\Program Files\Norton Internet Security\Engine\19.6.2.10\ccSvcHst.exe
O23 - Service: Intel(R) NMS (NMSSvc) - Intel Corporation - C:\WINDOWS\system32\NMSSvc.exe
O23 - Service: LiveShare P2P Server (RoxLiveShare) - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\SharedCOM8\RoxLiveShare.exe
O23 - Service: RoxMediaDB - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\SharedCOM8\RoxMediaDB.exe
O23 - Service: RoxUpnpRenderer (RoxUPnPRenderer) - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\SharedCom\RoxUpnpRenderer.exe
O23 - Service: RoxUpnpServer - Sonic Solutions - C:\Program Files\Roxio\Easy Media Creator 8\Digital Home\RoxUpnpServer.exe
O23 - Service: Roxio Hard Drive Watcher (RoxWatch) - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\SharedCOM8\RoxWatch.exe

--
End of file - 9903 bytes

Hello rtmccarron,

In case you missed it please see the FAQ which includes guidelines for this forum and instructions in post #2 on how to provide the preliminary "DDS" logs used for analysis.

http://forums.spybot.info/showthread.php?t=288

Then you'd need to start a new topic providing the logs requested so a volunteer analyst can advise you when available. :)

Best regards.