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The info at the link does not relate to removing the download directory from the "scan list".

OK So it sounds like removing the download directory from the "scan list" will fix this. Problem: How?

No. (I've not had access to any control on what it does or doesn't scan.)

The latest. When it did it the second time (consecutive), I downloaded the software again, in case the program on my computer had become corrupted. I did this Friday. It first occurred Monday...

When I run SPYBOT, it works fine until the very last item, the Downloads. Then it locks up.