ComboFix is not a general purpose cleaning tool and should only be run under the supervision of someone who has been trained and continues their education in its use.
Tools improperly used may cause Windows to become unstable.
However if one has run tools/fixes before requesting assistance please inform your helper, so that s/he is aware changes may have been made to the system and why. Running fixes before analysis can destroy evidence of an infection, leaving the malware difficult to detect.
That said, there is always risk involved in installing and removing any software. Even a fix that time has shown to be useful to thousands of users, can present problems to a few or be found to have a bug in development.
While best efforts are made to assist in removing infections safely, unexpected stuff can happen. It is advisable that you back up your important data before starting any clean up procedure. Neither Safer Networking Forums nor the Analyst providing the advice may be held responsible for any loss.
Microsoft MVP. Consumer Security 2006-2013
Please help us improve Spybot, download our distributed testing client