Microsoft.Windows.System

[Broken Hope]

Is there a reason why Spybot is detecting this? It's a setting I've changed myself

Microsoft.Windows.System: [SBI $CA5FA75C] Settings (Registry change, nothing done)
HKEY_USERS\Software\Microsoft\Windows\CurrentVersion\Policies\Explorer\NoShellSearchButton


--- Spybot - Search & Destroy version: 1.5 (build: 20070924) ---

2007-08-31 blindman.exe (1.0.0.6)
2007-08-31 SDMain.exe (1.0.0.4)
2007-10-04 SDUpdate.exe (1.0.7.4)
2007-08-31 SDWinSec.exe (1.0.0.8)
2007-09-24 SpybotSD.exe (1.5.1.16)
2007-08-31 TeaTimer.exe (1.5.0.9)
2007-10-23 unins000.exe (51.46.0.0)
2007-08-31 Update.exe (1.4.0.5)
2007-08-31 advcheck.dll (1.5.3.0)
2007-04-02 aports.dll (2.1.0.0)
2007-04-02 DelZip179.dll (1.79.5.3)
2007-08-31 SDHelper.dll (1.5.0.8)
2007-08-31 Tools.dll (2.1.2.0)
2007-11-07 Includes\Beta.sbi (*)
2007-11-06 Includes\Beta.uti
2007-11-07 Includes\Cookies.sbi (*)
2007-10-31 Includes\Dialer.sbi (*)
2007-11-07 Includes\DialerC.sbi (*)
2007-11-07 Includes\Hijackers.sbi (*)
2007-11-07 Includes\HijackersC.sbi (*)
2007-10-04 Includes\Keyloggers.sbi (*)
2007-11-07 Includes\KeyloggersC.sbi (*)
2007-11-07 Includes\Malware.sbi (*)
2007-11-07 Includes\MalwareC.sbi (*)
2007-10-24 Includes\PUPS.sbi (*)
2007-11-07 Includes\PUPSC.sbi (*)
2007-11-07 Includes\Revision.sbi (*)
2007-05-30 Includes\Security.sbi (*)
2007-11-07 Includes\SecurityC.sbi (*)
2007-11-07 Includes\Spybots.sbi (*)
2007-11-07 Includes\SpybotsC.sbi (*)
2007-11-06 Includes\Tracks.uti
2007-11-07 Includes\Trojans.sbi (*)
2007-11-07 Includes\TrojansC.sbi (*)
2008-12-24 Plugins\TCPIPAddress.dll

[Rosenfeld]

It's just flagging up the fact that the data is not at its expected default value. Since you changed it yourself, you can ignore it (you can also right click on it, exclude this detection from future scans).

Had it been changed by some malware, you would have been glad to have been notified.