I had the same issues as "samward" and several others with the "Win32.2Urface.bho" malware. I ran Spybot 3 times and found the malware 3 times. Spybot could not get rid of it. So, I tried booting up in safe mode, then running Spybot. Spybot found it again, fixed it, and I was able to purge it from the quarantine file (which I hadn't been able to do before.) After booting the computer up normally, I ran Spybot one more time and ... TA-DA... the malware was not found again! BTW, I'm using Windows7 and the free version of Spybot.