Malware removal help

[KingJohn630]

Hello,

I'm trying to fix my sis' comp and not having any luck. It seems to be infected with some kind of malware or virus. I cannot install or uninstall any programs. I cannot run programs such as Malwarebytes, not even in safe mode. Nothing happen when I click on it. I tried right-click and run as administrator.
Malwarebyte, AVG and McAfee Security Center are installed.
I tried running exeHelper.com and tdsskiller. Not logs were generated.
This is Windows 7.
There is an error when it boots up. Something regarding 16 bit application is unsupported. \\.\globalroot\systemroot\svchost.exe cannot start.
Any help will be appreciated.