Originally Posted by
PepiMK
@129260: Spybot-S&D always had some basic rootkit detection mechanisms, but the latest updates improved on three important fronts there.
Spybot-S&D usually detects threats in our database only; RootAlyzer just shows any things it identified as hidden, without relating them to known malware. So you could use RootAlyzer to detect even rootkits that are not known yet; but one of the new plugins for Spybot-S&D includes kind of a rootkit heuristics (which is not as generic though).
In summary: use RootAlyzer if Spybot-S&D hasn't found the culprit and you're suspecting an unlisted malware.