Immunization Problems

[Desasw23]

So I've been using Spybot for almost 8 years now. I would immunize my my browsers often but an issues arrives. The problem usually occurs when it begins to work on Firefox. I have gone through the process before using permissions.sqlite and changing it into host.perm1. (Or if there are two, deleting permissions.sqlite)Now the issue is new Firefox does not come with any of the two. I have set my current default settings so that I wont have any cookies saved.

Will immunization still work?

Is there another method to immunize Firefox.

Thanks