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Vista Security Center
The Windows Security Center included with Windows Vista has a dedicated entry for malware protection software.
Microsoft ships Windows Defender with Vista, however, Spybot-S&D can now easily integrate into the Vista Security Center; which will then monitor if Spybot-S&D is up-to-date and whether the permanent protection (TeaTimer) is running or not.
This update will only show on Vista systems, since previous Windows versions do not offer anti malware integration into WSC.
Download beta versions of above tools here