253 items looks like a lot,but Spybot also scans for usage tracks,so not everything found in your scan is necessarily bad:
http://www.safer-networking.org/faq/usage-tracks/
To tell if anything listed in the Spybot scan is a usage track or not,you can scroll over to the right and see what category it is listed as,or you can click on it with your mouse,and the category will show over to the left,if you're using anything above Spybot 1.6.2.
If you're using Spybot 1.6.2,tracks would show as green.
Also,some things could be tracking cookies,which would be a minimal threat.
If you think that what's being found isn't mainly tracks,please post back and let me know. :)