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Agreed. When you "immunize" Firefox, over 19,000 lines are added to your hostperm.1 file. This can have a pronounced negative effect on browsing/rendering speeds because that entire file is parsed...

I just installed on XP SP2, immunized and was left with unprotected items in IE - Software - Plugins, the same issue as in my original post which was about Vista.

There is another post about this...

I experienced your exact issue and posted about it here: http://forums.spybot.info/showthread.php?t=17557

The fix for me and another user was to "Undo" the immunizations (this may take awhile so...

FYI:
I got all the immunization protection entries enabled by using the "Undo" function to remove all protection and then simply clicking on "Immunize" which enabled every item including the ones...

I did try "Run as administrator" (when running SpyBot and when installing) but SpyBot still will NOT immunize all. This last time I uninstalled (I ran "undo" first) and reinstalled, and ran the...

Vista does NOT tell me I am not being allowed to operate at the administrative level of my computer. I have full administrative rights. I receive no message from Vista or Spybot.

I uninstalled,...

As Administrator on a Vista machine, I chose to immunize but 695 entries (IE - Software - Plugins, if I remember correctly) were not processed.

Thanks in advance.