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Oppressed and Spybot Helpers,

I have the exact same problem as Oppressed. I was infected by Spyaxe. By running the smitrem.exe, many files were deleted and my PC became stable.

I run Spyware...

I have Mcaffee Anti Virus software.

Mcaffee auto deleted the 3rd PUP referenced in my prior posting:

C:/System Volume Information/_restore{B37680B2-4E5D-BF30-83E44C588624}/RP2/A0000403.exe
...

Here is how I eliminated both smithfraud.c and Spyaxe.

I ran Spybot.
I installed and ran Spydoctor.
I cleaned up my Temp files (where there was a Spyaxe Installer)
I downloaded the smitRem.exe...

Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe...

Dear Fred 99,

I also got infected with SPYAXE.

By doing the following, I have eliminated most of the problems like popups and the flashing icon on the toolbar:

I ran Spybot
I ran Spyware...