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A new Version of Spybot have been released. Please download it and install it. Let us knew if the Problem still occurs.

So which Browser is not getting immunisated in your case?
Could you provide a Screenshot from the Immu-Wizzard?

What exactly does not apply?

Please have a look here: http://forums.spybot.info/showthread.php?p=438825#post438825

If this helps.

I guess it is again an issue from the changes made in Opera
They again charged sonething How they thread their stuff and Spybot cant yet handle this News staff.

Are u using the latest Version of Opera?

@winterb: Does only Opera not getting immunisated or all browser?

Please also try Kommunikation again after u disabled all ur other security-software and give Feedback

u are running a 64bit version of windows. spybot cannot handle 64bit-Versions correctly now, so immunisation status is not correctly.