Already posted it in the Wiki, but since a Wiki isn't useful to ask questions etc., I'm going to add it here as well:

Examples:Spectorsoft eBlaster 5 (Keylogger)

Code:
// info: OpenSBI example
// author: Patrick M. Kolla (PepiMK)
// date: 2008-05-23 (1.6)
// copyright: (c) 2008 Safer Networking Ltd. All rights reserved.
// count: 14

:: Spectorsoftware.eBlaster.5
// {Cat:Keylogger}{Cnt:1}
// {Det:patrick,2008-05-23}
RegyKey:"<$REG_CLASSID>",HKEY_CLASSES_ROOT,"\CLSID\","{2BE166ED-F16C-46de-B623-3575FD9B5D6D}"
RegyKey:"<$REG_CLASSID>",HKEY_CLASSES_ROOT,"\CLSID\","{4924E02A-C3A1-43ED-9EF2-28B8222039CC}"
RegyKey:"<$REG_CLASSID>",HKEY_CLASSES_ROOT,"\CLSID\","{8F3CA4AA-CD58-4424-8E77-C08801F1EA61}"
RegyKey:"<$REG_CLASSID>",HKEY_CLASSES_ROOT,"\CLSID\","{93AA1CB6-383A-49EF-B197-D31B4D577B90}"
RegyKey:"Hook",HKEY_CLASSES_ROOT,"\","Httpcmd","CLSID\={4924E02A-C3A1-43ED-9EF2-28B8222039CC}"
RegyKey:"<$REG_BHO>",HKEY_LOCAL_MACHINE,"\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Browser Helper Objects\","{93AA1CB6-383A-49EF-B197-D31B4D577B90}"
RegyValue:"<$REG_AUTORUN>",HKEY_LOCAL_MACHINE,"\SOFTWARE\Microsoft\Windows\CurrentVersion\ShellServiceObjectDelayLoad","Proftab","Proftab={8F3CA4AA-CD58-4424-8E77-C08801F1EA61}"
File:"<$FILE_LIBRARY>","<$SYSDIR>\xmlv2.dll","filesize=1052672,md5=A76C36A1BAA095A6D4C8A0E95582C089"
File:"<$FILE_EXE>","<$SYSDIR>\svrxp.exe","filesize=1552384,md5=7F02BE43B8759FA66BAA347FC22DC04B,setenv=eblaster5:yes"
File:"<$FILE_LIBRARY>","<$SYSDIR>\ipxstyle.dll","filesize=761856,md5=3AEBF1E8EC43169D23B710CB69DFC807"
File:"<$FILE_LIBRARY>","<$SYSDIR>\ipnt.dll","filesize=43998,md5=85CED0C1CE0F1367651A89E98743618E"
File:"<$FILE_LIBRARY>","<$SYSDIR>\camohcmp32.dll","filesize=114578,md5=0C943CA64C083C6A205D71C06706B62F"
File:"<$FILE_LIBRARY>","<$SYSDIR>\calv32.dll","filesize=577536,md5=53D9A64B4A60118915DBC96BEF49383A"
Directory:"<$DIR_APPDATA>","<$SYSDIR>\logmidi","isenv=eblaster5"
A detailed explanation on how one would go ahead to create this detection is available on the wiki link above; in this example we just used InCtrl5 and the OpenSBI editor.