Virus hijack my computer - denies access to everything from safer-networking, SPYBOT.

[T1m11]

Hello people,
I'm new here. My problem is as described briefly above; and so I have to ask for help from work computer.
The computer now sometimes stalls when I start and have to restart 2 or 3 times before WinXP opens. I can use the internet but very slowly and anything to do with SPYBOT sites are denied.
Can anyone help???

Edit: Before the virus strikes I have SPYBOT and Lavasoft Adaware which work for me for years but right now and can't open the existing SPYBOT. I can use Lavasoft but can't update it. I tried uninstall and reinstall SPYBOT. Doesn't work either. I think I have a virus or malware that hates spybot.