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I too have a problem with Spybot 1.4., running under XP2.
Until recently no problem, but now when Spybot is called (no other programs running) it fails to load and just hangs, preventing any other program from loading, including Task Manager. The "START/ Turn Off" option also fails to display after 2 or 3 other keybd/mouse actions are taken, and must repower.
I removed most Startup entires in MSConfig and discovered that if DUMeter v3.5 (a download rate meter from Hagel) was NOT loaded, then Spybot would run OK, even if all the other Startup entries were restored. So there appears to be a conflict between these 2 programs.
I took the advice offered on this thread to clean the heat sink of the PC processor, to ensure that it would not overheat. It was not dirty anyway , so no improvement in my case.
Can anyone offer any suggestions?
Brian