Go ahead and run Combofix again, but I am leaning towards your Master Boot Record being infected, lets see if CF will calm things down, run it this time with this script, I may be getting ahead of myself here but since your system is in such bad shape we need to forge ahead.
Open Notepad Go to Start> All Programs> Assessories> Notepad ( this will only work with Notepad )and copy all the text inside the Codebox by highlighting it all and pressing CTRL C on your keyboard, then paste it into Notepad, make sure there is no space before and above Fcopy::
Code:
FCopy::
C:\WINDOWS\system32\dllcache\spoolsv.exe | C:\WINDOWS\System32\spoolsv.exe
C:\WINDOWS\system32\dllcache\wscntfy.exe | C:\WINDOWS\System32\wscntfy.exe
Save this as CFScript to your desktop.
Then drag the CFScript into ComboFix.exe as you see in the screenshot below.
This will start ComboFix again. After reboot, (in case it asks to reboot), post the contents of Combofix.txt in your next reply.