Yes,you should only need to have Spybot remove those 6 items by pressing Fix selected.No need to worry about removing them any other way,unless they were to return after you do another scan.
No need to worry about the other entries Spybot found before you did the system restore,the only way those should come back is if you were to Undo the System Restore,so all should be good there.
I just glanced quickly,but I believe Youtube downloader does bundle a Spigot-based YTD Video Toolbar with it when you download Youtube downloader,and the YTD Video Toolbar needs to be declined when installing if you would rather not have it.I couldn't find anything anywhere that Youtube downloader by itself,alone,was malware/adware,though I didn't get a good,thorough look at things,either.So if you did decide to reinstall Youtube downloader,you might want to decline anything offered along with the install.Of course,if you have no need of Youtube downloader any longer,and wish to leave it uninstalled,that's an ok choice,too.