You posted on the 14th. The weekly updates usually are released on Wednesday's, and the 14th was the day after. If this error started happening very recently, I wonder if it might be related to one of the weekly updates somehow. I'm not sure if that's possible, but it would be worth opening a support ticket to ask about the error.
Could you please contact Team Spybot using this form?
https://www.safer-networking.org/support/#contactform
In the meantime, until you hear back from them, you could try putting in a dvd in the dvd drive while you do a Spybot Scan as a temporary solution. It may not work, as I'm not sure what drive Spybot is attempting to scan, but it might be worth a try. This is what some people did when this error came up before.