I've recently been sent a free upgrade from TrendMicro for Internet Security 2007 from PC-Cillain 2006. I've got several issues I've found with it. According to a poster on Wilders Security Forums, he had contact Trend Micro about these issues, which include high memory and CPU usage and problems with their spyware applications, and their tech support told him to uninstall TrendMicro, delete it's program folder, then undo immunizations for Spybot and uninstall Spybot before reinstalling Trend Micro IS2007. Evidently this resolved his issues. Are there any known conflicts between these two products? I never had any issues with their 2006 software.