Unfortunately after fixing all the malware and rootkits detected by Spybot S&D, I now cannot run my Windows OS because there's a program that cannot exectute:

WNNT\System32\ntvdm.exe opens as a black window on the desktop wallpaper before desktop icons have appeared and just remains there frozen, and I cannot get beyond that point.

But I CAN reboot in safe mode, which is what I'm doing now. Any suggestions on how to be able to operate my OS in normal mode?