Originally Posted by
Mike...
I created a new profile and added everything anew instead of porting things over from the previous profile and I still have this issue with both Spybot and SpywareBlaster...
Edit: Okay, this doesn't appear to be a profile issue. Go to Tools > Options > Privacy tab. If you have "Clear history when firefox closes" checked, you can access the Settings button next to it. When "Site Preferences" is checked, immunization will be undone each time "History is cleared". Uncheck "Site Preferences" to keep all immunization.