We're here to help. :santa:
A corrupted setup file, means that there's something wrong with the file itself, in simple terms. Like there's bad data or something that's missing.
Please download a fresh copy of Spybot-Search&Destroy from SaferNetworking Severs:
http://www.safer-networking.org/en/mirrors/index.html
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Good luck.
I'm having trouble understand what you are talking about. Please clarify.Spybot160 as well as "reset settings" and "miniremoval of SmartKiller".