willywinky,
When you post asking for assistance it helps to give as much information as you can, particularly what version of Spybot and what operating system you are using.
The S-1-5-18, S-1-5-19 and S-1-5-20 are Local Service, Network Service and System accounts.
Spybot discontinued immunising these accounts in late 2007 because they are rarely if ever used as operational accounts. The fact that they are appearing in the form shown in your screen shot suggests you are using a outdated version of the program.
The solution is to un-immunise (undo the immunisations), if you are using Teatimer turn it off, then uninstall the program. Please read
http://www.spybot.info/en/faq/56.html and after uninstalling, use the "This very small Fix"
Download and install the current version from one of the sites at
http://www.spybot.info/en/mirrors/index.html. During the installation take careful note of the options offered. If you don't want Spybot in your right click menu make the choice during the installation. I recommend NOT getting the updates until after the program has been installed, and NOT making Teatimer active until after the first scan (and any fixes) have been made.
Hope this helps