Is there any chance you may have renamed the default Spybot installation folder after you had installed Spybot?
It's probably located here:
C:\Program Files\Spybot - Search & Destroy
Could you post your system startup list?
To do that,you'd open Spybot,select mode up top,then Advanced Mode,then over to the left,select Tools,then System Startup.Then click Export,save the startup report somewheres,then copy and paste it here.